Document Detail

Non-immune hydrops fetalis caused by herpes simplex virus type 2 in the setting of recurrent maternal infection.
MedLine Citation:
PMID:  24071962     Owner:  NLM     Status:  In-Data-Review    
We report a case of non-immune hydrops fetalis (NIHF) caused by herpes simplex virus type 2 (HSV-2) in an infant whose mother had recurrent HSV-2 infection. In spite of prematurity, severe disseminated infection and hydrops, the infant survived and was neurologically intact. HSV-2-induced NIHF is extremely rare, particularly in the setting of recurrent maternal infection, and this case is, to our knowledge, the first report of a surviving infant. HSV-2 should be considered in the differential diagnosis of NIHF and early initiation of empiric acyclovir therapy is recommended in this setting, pending the results of virologic diagnostic tests.
K M Pfister; M R Schleiss; R C Reed; T N George
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  33     ISSN:  1476-5543     ISO Abbreviation:  J Perinatol     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2013-09-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  817-20     Citation Subset:  IM    
Division of Neonatology, Department of Pediatrics, University of Minnesota Amplatz Children's Hospital, Minneapolis, MN, USA.
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