Document Detail

Non-homogeneous hyperechogenic pattern 3 days after embryo transfer is associated with lower pregnancy rates.
MedLine Citation:
PMID:  10783354     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to investigate the relationship between mid-luteal phase echo patterns and IVF-embryo transfer outcome in women who have demonstrated adequate endometrial development by the late proliferative phase. A prospective study was carried out of 86 patients undergoing IVF-embryo transfer and 86 patients undergoing frozen embryo transfer who all underwent sonographic monitoring of the endometrium 3 days after embryo transfer. The cycles were classified into two groups: those with the homogeneous hyperechogenic (HH) pattern and those without it. The women who had an HH pattern had higher clinical pregnancy (32.8 versus 10.7%, P < 0.05) and implantation rates in stimulated cycles (14.3 versus 4.1%, P < 0.05 respectively) than those that did not. There was no significant difference in the clinical pregnancy or implantation rates by echo pattern (18.2 and 8.1% for non-HH and 18. 7 and 8.0% for HH respectively) in frozen embryo transfer cycles. These data demonstrate that in embryo transfer cycles where ovarian stimulation was used, there were decreased pregnancy and implantation rates in cycles where the HH pattern was not observed 3 days after transfer. The failure of the endometrium to display this pattern may indicate some endometrial abnormality resulting in implantation defects.
J H Check; C Dietterich; D Lurie
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  15     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  2000 May 
Date Detail:
Created Date:  2000-07-20     Completed Date:  2000-07-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1069-74     Citation Subset:  IM    
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, New Jersey, USA.
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MeSH Terms
Embryo Implantation
Embryo Transfer*
Endometrium / anatomy & histology,  physiology*,  ultrasonography*
Fertilization in Vitro
Infertility, Female / therapy
Luteal Phase / physiology*
Maternal Age
Ovulation Induction
Pregnancy Rate*
Prospective Studies
Sperm Injections, Intracytoplasmic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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