Document Detail

Non-enzymic interactions of nicotinamide adenine dinucleotide, of some of its synthetic analogues and other compounds with orthophosphate.
MedLine Citation:
PMID:  40296     Owner:  NLM     Status:  MEDLINE    
Changes in the ultraviolet (UV) absorption spectra of nicotinamide adenine dinucleotide (NAD), of its synthetic analogues, and of adenosine and its derivatives in the presence of high concentrations of orthophosphate were studied. The role of the carboxamide group of the nicotinamide moiety of NAD on these spectral changes was investigated by replacing that group with an acetyl or aldehyde group. The effect of the 6-amino group of the purine was investigated by studying the interaction of deamino-NAD and various adenosine derivatives with orthophosphate. 2,4-Dinitrophenol was also found to give a charge transfer complex with phosphate. Molar extinction coefficients (E) and association constants (K) of these charge transfer reactions were determined.
F Ungar; B Ungar; S G Alivisatos; A D Mosnaim; M E Wolf
Related Documents :
19081716 - Optimization of a series of 4,6-bis-anilino-1h-pyrrolo[2,3-d]pyrimidine inhibitors of i...
11257526 - Synthesis of (di)adenosine polyphosphates by non-ribosomal peptide synthetases (nrps).
1018716 - Acid-soluble purine and pyrimidine derivatives in cow's milk produced on normal feed an...
6163466 - Thymidine catabolism and the reutilization of its degradative products in tetrahymena p...
16009226 - Inhibition of cold rolled steel corrosion by tween-20 in sulfuric acid: weight loss, el...
18626816 - Volatile constituents of aerial parts of three endemic centaurea species from turkey: c...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Research communications in chemical pathology and pharmacology     Volume:  25     ISSN:  0034-5164     ISO Abbreviation:  Res. Commun. Chem. Pathol. Pharmacol.     Publication Date:  1979 Aug 
Date Detail:
Created Date:  1979-12-27     Completed Date:  1979-12-27     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0244734     Medline TA:  Res Commun Chem Pathol Pharmacol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  395-8     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adenine Nucleotides
Chemical Phenomena
Hydrogen-Ion Concentration
NAD* / analogs & derivatives*
Reg. No./Substance:
0/Adenine Nucleotides; 0/Phosphates; 53-84-9/NAD; 58-61-7/Adenosine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Digital computer analysis of the electromyogram: preliminary report (author's transl)
Next Document:  12-Hour simultaneous registration of acid reflex and peristaltic activity in the oesophagus. A study...