| Non-contact spectroscopic determination of large blood volume fractions in turbid media. | |
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MedLine Citation:
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PMID: 21339884 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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We report on a non-contact method to quantitatively determine blood volume fractions in turbid media by reflectance spectroscopy in the VIS/NIR spectral wavelength range. This method will be used for spectral analysis of tissue with large absorption coefficients and assist in age determination of bruises and bloodstains. First, a phantom set was constructed to determine the effective photon path length as a function of μ(a) and μ(s)' on phantoms with an albedo range: 0.02-0.99. Based on these measurements, an empirical model of the path length was established for phantoms with an albedo > 0.1. Next, this model was validated on whole blood mimicking phantoms, to determine the blood volume fractions ρ = 0.12-0.84 within the phantoms (r = 0.993; error < 10%). Finally, the model was proved applicable on cotton fabric phantoms. |
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Authors:
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Rolf H Bremmer; Stephen C Kanick; Nick Laan; Arjen Amelink; Ton G van Leeuwen; Maurice C G Aalders |
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Publication Detail:
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Type: Journal Article Date: 2011-01-24 |
Journal Detail:
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Title: Biomedical optics express Volume: 2 ISSN: 2156-7085 ISO Abbreviation: Biomed Opt Express Publication Date: 2011 |
Date Detail:
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Created Date: 2011-02-22 Completed Date: 2011-07-14 Revised Date: 2011-07-25 |
Medline Journal Info:
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Nlm Unique ID: 101540630 Medline TA: Biomed Opt Express Country: United States |
Other Details:
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Languages: eng Pagination: 396-407 Citation Subset: - |
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