Document Detail


Non-coding transcription SETs up regulation.
MedLine Citation:
PMID:  23147798     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
An abundance of long non-coding RNA (lncRNA) present in most species from yeast to human are involved in transcriptional regulation, dosage compensation and imprinting. This underscores the importance of lncRNA as functional RNA despite the fact that they do not produce proteins. Two recent papers in Cell have demonstrated that transcription of the non-conserved lncRNAs, but not the RNAs themselves, is necessary to introduce co-transcriptional regulatory histone marks to regulate gene expression.
Authors:
Swaminathan Venkatesh; Jerry L Workman
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-13
Journal Detail:
Title:  Cell research     Volume:  -     ISSN:  1748-7838     ISO Abbreviation:  Cell Res.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9425763     Medline TA:  Cell Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Stowers Institute for Medical Research, 1000 E. 50th Street, Kansas City, MO 64110, USA.
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