Document Detail

Non-coding transcription SETs up regulation.
MedLine Citation:
PMID:  23147798     Owner:  NLM     Status:  MEDLINE    
An abundance of long non-coding RNA (lncRNA) present in most species from yeast to human are involved in transcriptional regulation, dosage compensation and imprinting. This underscores the importance of lncRNA as functional RNA despite the fact that they do not produce proteins. Two recent papers in Cell have demonstrated that transcription of the non-conserved lncRNAs, but not the RNAs themselves, is necessary to introduce co-transcriptional regulatory histone marks to regulate gene expression.
Swaminathan Venkatesh; Jerry L Workman
Related Documents :
22506888 - Exosomal rna as biomarkers and the therapeutic potential of exosome vectors.
20832068 - Calcitonin gene-related peptide inhibits angiotensin ii-induced endothelial progenitor ...
23136298 - Sirt6 is decreased with preterm labor and regulates key terminal effector pathways of h...
22524308 - Hepatitis b virus directly promotes collagen i expression of lx-2 cells without infecti...
23845988 - Erbb4 is an upstream regulator of ttf-1 fetal mouse lung type ii cell development in vi...
10625538 - The drosophila sox gene, fish-hook, is required for postembryonic development.
Publication Detail:
Type:  Journal Article     Date:  2012-11-13
Journal Detail:
Title:  Cell research     Volume:  23     ISSN:  1748-7838     ISO Abbreviation:  Cell Res.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-03-04     Completed Date:  2013-09-05     Revised Date:  2014-03-07    
Medline Journal Info:
Nlm Unique ID:  9425763     Medline TA:  Cell Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  311-3     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Chromatin / metabolism
Gene Expression Regulation / genetics,  physiology
Histones / metabolism
RNA, Long Noncoding / genetics,  metabolism*
Reg. No./Substance:
0/Chromatin; 0/Histones; 0/RNA, Long Noncoding

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Zscan4 promotes genomic stability during reprogramming and dramatically improves the quality of iPS ...
Next Document:  Microchannel-induced change of chemical wave propagation dynamics: importance of ratio between the i...