Document Detail

Non-classic congenital adrenal hyperplasia due to 21-hydoxylase deficiency as a cause of infertility and miscarriages.
MedLine Citation:
PMID:  20389322     Owner:  NLM     Status:  MEDLINE    
Miscarriages and infertility can be presenting symptoms of non-classic congenital adrenal hyperplasia (NCAH). Two sisters are described with fertility issues and multiple miscarriages occurring up to 20 weeks of pregnancy. After diagnosing NCAH due to 21-hydroxylase deficiency and initiating glucocorticoid treatment,conception occurred within 3 months and uneventful pregnancies and deliveries ensued.
Henrik Falhammar
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-04-09
Journal Detail:
Title:  The New Zealand medical journal     Volume:  123     ISSN:  1175-8716     ISO Abbreviation:  N. Z. Med. J.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-14     Completed Date:  2010-05-04     Revised Date:  2011-08-05    
Medline Journal Info:
Nlm Unique ID:  0401067     Medline TA:  N Z Med J     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  77-80     Citation Subset:  IM    
Department of Endocrinology, Cairns Base Hospital, PO Box 902, Cairns, QLD 4870, Australia.
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MeSH Terms
Abortion, Spontaneous / etiology*
Adrenal Hyperplasia, Congenital / complications*,  diagnosis*,  drug therapy
Glucocorticoids / therapeutic use
Infertility, Female / etiology*
Prednisolone / therapeutic use
Steroid 21-Hydroxylase / genetics
Reg. No./Substance:
0/Glucocorticoids; 50-24-8/Prednisolone; EC protein, human; EC 21-Hydroxylase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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