Document Detail


Non-alcoholic steatohepatitis and cirrhosis in young adult patients with hypothalamic-pituitary dysfunction.
MedLine Citation:
PMID:  23392740     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: In rare cases, hypothalamic-pituitary dysfunction can be associated with an extraordinarily active non-alcoholic steatohepatitis (NASH) and subsequent liver cirrhosis. CASE REPORT: The two young adult patients described in this report presented with NASH together with advanced liver fibrosis and cirrhosis 5 and 19 years, respectively after resection of a craniopharyngeoma. CONCLUSIONS: In young patients and children with active steatohepatitis, an association with hypothalamic-pituitary dysfunction should be excluded. Especially hypothalamic-pituitary-related NASH tends to develop rapidly into liver cirrhosis.
Authors:
D Goltz; K Schötta; H Zhou; H-P Fischer
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-9
Journal Detail:
Title:  Der Pathologe     Volume:  -     ISSN:  1432-1963     ISO Abbreviation:  Pathologe     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8006541     Medline TA:  Pathologe     Country:  -    
Other Details:
Languages:  GER     Pagination:  -     Citation Subset:  -    
Affiliation:
Institut für Pathologie, Universität Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Deutschland.
Vernacular Title:
Nichtalkoholische Steatohepatitis mit Zirrhose bei jungen Erwachsenen mit hypothalamisch-hypophysärer Dysfunktion.
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