| Non-Sarcoid Granulomatous Myopathy: Two Cases and a Review of Literature. | |
| | |
MedLine Citation:
|
PMID: 23311755 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Abstract Granulomatous myopathy is an uncommon skeletal muscles disorder. It can develop in association with other granuloma-forming diseases and is then considered a secondary myopathy or, less frequently, a primary disorder for which no etiology is identified. Studies of granulomatous myopathies have focused on examining the differences between primary and secondary diseases. Herein we describe two cases of non-sarcoid granulomatous myopathies, for which diagnostic work-up did not reveal an underlying granuloma-causing pathology. The patients exhibited similar histopathological characteristics in skeletal muscle biopsies. However, they had different clinical presentations and therapeutic responses. Specifically, one patient had distal muscle weakness with a poor response to immunosuppressive treatment, whereas the other had a more proximal muscle weakness distribution and a very good response to treatment with corticosteroids and azathioprine, resulting in remission. More studies are warranted to further characterize the clinical course and effect of different treatment modalities on non-sarcoid granulomatous myopathy. |
| | |
Authors:
|
Sina Jasim; Aziz Shaibani |
Related Documents
:
|
23317635 - Sonography assessment of the median nerve during cervical lateral glide and lateral fle... 18647755 - Therapeutic angiogenesis with placental growth factor improves exercise tolerance of is... 21161685 - Danon disease: intrafamilial phenotypic variability related to a novel lamp-2 mutation. 7270705 - Filling of microcirculation in skeletal muscles during timed india ink perfusion. 9553745 - Cortical representation of proximal and distal arm muscles as assessed by focal transcr... 6668765 - Double-peaked positive chronotropic responses of isolated and cross-perfused dog atria ... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2013-1-13 |
Journal Detail:
|
Title: The International journal of neuroscience Volume: - ISSN: 1563-5279 ISO Abbreviation: Int. J. Neurosci. Publication Date: 2013 Jan |
Date Detail:
|
Created Date: 2013-1-14 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0270707 Medline TA: Int J Neurosci Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
1Saint Louis University , Saint Louis , MO. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cucumber-like vanadium pentoxide/poly-3,4-ethylenedioxythiophene& manganese oxide nanowires with enh...
Next Document: Designing a placebo device: involving service users in clinical trial design.