Document Detail


Non-Q-wave myocardial infarction: pathophysiology, prognosis, and therapeutic strategy.
MedLine Citation:
PMID:  2567144     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Non-Q-wave infarction, formerly referred to as nontransmural infarction, is usually associated with less myocardial necrosis and a lower in-hospital mortality than Q-wave or transmural infarction. Despite the initially favorable prognosis, however, long-term survival of patients after non-Q-wave infarction is similar to or even shorter than that after Q-wave infarction. It is now well documented that patients with non-Q-wave infarction are more prone to reinfarction, which usually occurs in the same area as the original injury. Since extensive damage from recurrent myocardial necrosis has a considerable deleterious effect on long-term survival, patients with non-Q-wave infarction would be expected to benefit from prophylactic treatment that prevents reinfarction. Indeed, this subset of patients appears to provide a unique opportunity to modify favorably the natural history of ischemic heart disease.
Authors:
R S Gibson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Annual review of medicine     Volume:  40     ISSN:  0066-4219     ISO Abbreviation:  Annu. Rev. Med.     Publication Date:  1989  
Date Detail:
Created Date:  1989-06-27     Completed Date:  1989-06-27     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  2985151R     Medline TA:  Annu Rev Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  395-410     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville 22908.
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MeSH Terms
Descriptor/Qualifier:
Adrenergic beta-Antagonists / therapeutic use*
Electrocardiography
Humans
Myocardial Infarction / mortality,  physiopathology,  prevention & control*
Platelet Aggregation Inhibitors / therapeutic use*
Prognosis
Recurrence
Chemical
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Platelet Aggregation Inhibitors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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