Document Detail


Non-invasive flow measurement of a rotary pump ventricular assist device using quantitative contrast echocardiography.
MedLine Citation:
PMID:  20206830     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Many implantable ventricular assist devices (VADs) have no direct measurement of pump output. The aim of this study was to test the hypothesis that quantitative contrast echocardiography can be used to measure VAD output. METHODS: Contrast-enhanced Doppler velocity-time integral (VTI) was measured in the VAD inlet and outlet cannulae. Doppler flow (Doppler Q=Doppler VTIxcannula area) was compared with measured flow (Q). A total of 130 flow measurements were made (at 6400 and 12,000 rpm). RESULTS: Doppler Q in the outflow and inflow cannulae showed an excellent correlation with measured Q (outlet Doppler Q=1.0052 xQ+0.048, R2=0.9865; inlet Doppler Q=1.5043 xQ+0.003, R2=0.9904), but inlet Doppler Q was 50% higher. Correcting for the flow profile of the conical inlet tube yielded excellent correlation (inlet Doppler Q=1.0029 xQ+0.002, R2=0.9904). CONCLUSION: Noninvasive Doppler flow techniques can be used to accurately measure VAD flow, but the flow profile in the cannula needs to be taken into account.
Authors:
Karl Q Schwarz; Sachin S Parikh; Xucai Chen; David J Farrar; Sherry Steinmetz; Sridevi Ramamurthi; William Hallinan; H Todd Massey; Leway Chen
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  23     ISSN:  1097-6795     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-08     Completed Date:  2010-06-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  324-9     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved.
Affiliation:
University of Rochester Medical Center, Rochester, New York 14642, USA. karl_schwarz@urmc.rochester.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Blood Flow Velocity
Computer Simulation
Contrast Media*
Coronary Circulation / physiology*
Feasibility Studies
Heart Ventricles / ultrasonography*
Heart-Assist Devices*
Humans
Models, Cardiovascular*
Rheology / methods*
Ventricular Function, Left / physiology*
Ventricular Premature Complexes
Chemical
Reg. No./Substance:
0/Contrast Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Role of M-mode Technique in Today's Echocardiography.
Next Document:  HIV-1 gp41 Fusion Intermediate: A Target for HIV Therapeutics.