Document Detail

Non-Hodgkin lymphoma of the breast: imaging characteristics and correlation with histopathologic findings.
MedLine Citation:
PMID:  8208929     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To determine the imaging characteristics of non-Hodgkin lymphoma (NHL) of the breast and correlate these findings with histopathologic subtype. MATERIALS AND METHODS: The authors retrospectively reviewed records in 32 cases of histologically proved NHL in 29 women. Mammography was performed before biopsy in all cases, and breast sonography was performed before biopsy in eight. RESULTS: Mammary NHL was primary in 21 of the 32 cases (66%) and secondary in 11 (34%). Mammography revealed a solitary, uncalcified mass in 22 cases (69%), multiple masses in three (9%), and diffuse increased opacity with skin thickening in three (9%). Four cases (13%) had normal findings. Seven of the eight sonograms revealed masses, which were solitary in five and multiple in two. Histologic examination showed diffuse NHL in 26 cases (81%) and follicular NHL in six (19%). No mammographic or sonographic features were identified that helped distinguish primary from secondary disease or follicular from diffuse NHL. CONCLUSION: Although the imaging characteristics may suggest the possibility of breast NHL, none of the findings are pathognomonic. The imaging pattern of mammary NHL is unrelated to its histopathologic subtype.
L Liberman; C S Giess; D D Dershaw; D C Louie; B M Deutch
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  192     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1994 Jul 
Date Detail:
Created Date:  1994-07-12     Completed Date:  1994-07-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  157-60     Citation Subset:  AIM; IM    
Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
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MeSH Terms
Aged, 80 and over
Breast Neoplasms / pathology,  radiography*,  ultrasonography
Lymphoma, Follicular / pathology,  radiography,  ultrasonography
Lymphoma, Non-Hodgkin / pathology,  radiography*,  ultrasonography
Middle Aged
Retrospective Studies
Ultrasonography, Mammary

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