Document Detail


Non-HIV Kaposi's sarcoma: a review and therapeutic perspectives.
MedLine Citation:
PMID:  23017657     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
"Classic" Kaposi's sarcoma (CKS) not related to HIV is a multifocal angioproliferative neoplasm that is linked to human herpesvirus. CKS is a cutaneous cancer frequently occurring with an indolent course. However, it can compromise the quality of life by causing pain, disfigurement and functional disability. For this reason, the main treatment goals are not only to reduce the cutaneous lesions but also to alleviate organ involvement and psychological stress by delaying disease progression and ultimately cure. This report summarizes systemic treatment options of CKS, including chemotherapy, immunotherapy and anti-HHV8 therapy. In addition, this review will focus on the recent understanding of carcinogenesis and consequently highlight potential "targeted" therapeutic interventions.
Authors:
Yousra Akasbi; Ahmad Awada; Samia Arifi; Nawfal Mellas; Omar El Mesbahi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-28
Journal Detail:
Title:  Bulletin du cancer     Volume:  -     ISSN:  1769-6917     ISO Abbreviation:  Bull Cancer     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0072416     Medline TA:  Bull Cancer     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Hassan II University Hospital, Medical Oncology Department, 19, rue Jebel Zalagh 2 Narjiss C, 30000 Fez, Morocco, University Libre of Brussels, Institut Jules-Bordet, Medical Oncology Clinic, Brussels, Belgium.
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