| Nomogram for determining lower limit of the sural response. | |
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MedLine Citation:
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PMID: 20097608 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Age and height influence on sural sensory nerve action potential (SNAP) have been studied separately. Our aim was to develop an equation for predicting the lower normal limits as a function of both these factors. METHODS: One hundred fifty-eight healthy volunteers, 63 male, with mean age 45.8 and mean height 167.3 without symptoms or signs of peripheral neuropathy participated in the study. The sural SNAP was recorded at the level of the ankle joint, just posterior to the lateral malleolus, using surface electrodes. Antidromic supramaximal stimulation was performed 13 cm proximally at the posterior midcalf. RESULTS: The mean sural SNAP amplitude was 19.9+/-6.89 microV. Pearson linear correlation showed a negative correlation of the SNAP amplitude with age (R=-0.22, p=0.005) and height (R=-0.19, p=0.03). The multiple linear regression model was applied for both parameters of age and height with SNAP amplitude as the dependent parameter, producing the following equation: SNAP amplitude=62.45-0.1447 x Age-0.2147 x Height. CONCLUSIONS: Using our normal data, the computed lower limits of the 95% prediction interval for the sural SNAP amplitude of an individual subject, depending on his age and height, were calculated. SIGNIFICANCE: The individualized normal values provided by our equation are essential for the correct interpretation of sural nerve studies. |
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Authors:
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P Kokotis; D Mandellos; A Papagianni; N Karandreas |
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Publication Detail:
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Type: Journal Article Date: 2010-01-25 |
Journal Detail:
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Title: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Volume: 121 ISSN: 1872-8952 ISO Abbreviation: Clin Neurophysiol Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-08 Completed Date: 2010-03-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883319 Medline TA: Clin Neurophysiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 561-3 Citation Subset: IM |
Copyright Information:
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2010. Published by Elsevier Ireland Ltd. |
Affiliation:
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University of Athens, Eginition Hospital 72-74 Vas. Sofias Avenue, Athens 11528, Greece. pkokotis@med.uoa.gr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Action Potentials
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physiology* Adolescent Adult Age Factors Aged Aged, 80 and over Body Height / physiology Electrophysiology / methods Female Humans Male Middle Aged Neural Conduction / physiology* Predictive Value of Tests Reaction Time / physiology Reference Values Sural Nerve / physiology* Young Adult |
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