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Noise-induced hearing loss: From animals to humans.
MedLine Citation:
PMID:  20330063     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Exposure to noise can result in neural swelling, mechanical damage, andor a toxic accumulation of free radicals. The type and extent of the pathology, the amount of hearing loss, and the permanence of the hearing loss all vary with the level and duration of the noise insult. In addition, noise exposures in which sound level rapidly changes over time are more harmful than relatively constant level exposures. These relationships have been carefully worked out in animal models, and key findings will be reviewed. Evaluating the effects of noise on the human inner ear is more challenging. Exposures in the work place and other real-world environments can be challenging to control, and in those studies evaluating long-term effects of noise, the subjects are exposed to variable non-study noise sources. Exposures in the laboratory that induce temporary changes in human hearing carry their own challenges. In this lecture, we will discuss various human models for studies on the effects of noise, and we will present new data on temporary hearing changes in human subjects that listen to music with digital audio players. Several metrics used to measure the effects of noise will be discussed.
Authors:
Colleen Le Prell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the Acoustical Society of America     Volume:  127     ISSN:  1520-8524     ISO Abbreviation:  J. Acoust. Soc. Am.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503051     Medline TA:  J Acoust Soc Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1754     Citation Subset:  IM    
Affiliation:
Dept. of Communicative Disord., Univ. of Florida, Box 100174, Gainesville, FL 32610, colleeng@phhp.ufl.edu.
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