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Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer.
MedLine Citation:
PMID:  24952169     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: To determine whether the nodule and eminence on the frenulum labii superioris, location of Yinjiao (DU28) according to the meridian theory, could be used to prognosticate the recurrence of patients with colorectal cancer.
METHODS: The data of 101 patients with colorectal cancer in Tianjin Medical University Cancer Institute and Hospital from May 2011 to November 2011 was analyzed. The photos of all patients' frenulum labii superioris were taken. Nodule and eminence on frenulum labii superioris were the positive standard. Biopsy and pathological testing for the nodule were carried out on one patient with large nodule on frenulum labii superioris.
RESULTS: Patients with positive frenulum labii superioris had a higher risk of recurrence and/or metastasis than patients with negative frenulum labii superioris. There were no significant differences in diagnosis of recurrence and/or metastasis between the status of frenulum labii superioris and the traditional diagnostic criteria (P =0.238). The Kappa was 0.606 (P <0.001). The sensitivity was 76.0% and the specificity was 85.4%. The pathological report demonstrated that the nodule on frenulum labii superioris was mucosal excrescence with normal structure.
CONCLUSION: Nodule and eminence on frenulum labii superioris are potential diagnostic markers for metastatic colorectal cancer.
Authors:
Rui Cao; Li-Ping Wang; Jia-Dong Chi; Xiong-Zhi Wu
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-6-21
Journal Detail:
Title:  Chinese journal of integrative medicine     Volume:  20     ISSN:  1672-0415     ISO Abbreviation:  Chin J Integr Med     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-6-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101181180     Medline TA:  Chin J Integr Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  416-419     Citation Subset:  -    
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