Document Detail


Nodular lymphoid hyperplasia of the terminal ileum: report of a case and the findings of an immunological analysis.
MedLine Citation:
PMID:  8782302     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The immunological and immunohistochemical characteristics of a patient with nodular lymphoid hyperplasia (NLH) of the terminal ileum were investigated pre- and post-operatively. The patient presented with diarrhea, lower abdominal pain, and weight loss, and an abdominal X-ray following barium enema revealed multiple small nodules in the terminal ileum which were subsequently confirmed to be NLH by histological examination. Preoperatively, although the serum immunoglobulin levels were normal, the T-cell responses in the peripheral blood, including the phytohemagglutinin (PHA)-blastogenesis and the T4/T8 ratio, were impaired. However, following an ileocecal resection, the PHA-blastogenesis became augmented and the T4/T8 ratio recovered to within the normal range. The immunohistochemical findings revealed a more marked accumulation of T cells in the interstitium around the hyperplastic follicles than in the interstitium of the normal intestine.
Authors:
H Yamaue; H Tanimura; K Ishimoto; Y Morikawa; K Kakudo
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Surgery today     Volume:  26     ISSN:  0941-1291     ISO Abbreviation:  Surg. Today     Publication Date:  1996  
Date Detail:
Created Date:  1996-10-25     Completed Date:  1996-10-25     Revised Date:  2006-08-03    
Medline Journal Info:
Nlm Unique ID:  9204360     Medline TA:  Surg Today     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  431-4     Citation Subset:  IM; X    
Affiliation:
Department of Gastroenterological Surgery, Wakayama Medical School, Japan.
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MeSH Terms
Descriptor/Qualifier:
CD4-CD8 Ratio
Giant Lymph Node Hyperplasia / immunology*,  surgery
Humans
Ileal Diseases / immunology*,  surgery
Immunohistochemistry
Lymphocyte Activation
Male
Middle Aged
T-Lymphocytes / immunology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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