Document Detail

Nocturnal ultrasound measurements of optic nerve sheath diameter correlate with intracranial pressure in children with craniosynostosis.
MedLine Citation:
PMID:  22929269     Owner:  NLM     Status:  MEDLINE    
Children with craniosynostosis are at risk for increased intracranial pressure, and additional possibilities to screen for increased intracranial pressure are required. The authors' aim was to use ultrasound measurements of the optic nerve sheath to understand and express the variability of intracranial pressure in syndromic craniosynostosis. Therefore, five pediatric patients with craniosynostosis underwent invasive 24-hour intracranial pressure monitoring and simultaneous optic nerve sheath measurements. In three patients, the intracranial pressure was abnormal, and during the second half of the night, the optic nerve sheath was increased in all three patients. The optic nerve sheath diameter changes during the night and is as dynamic as the intracranial pressure. To the best of their knowledge, the authors are the first to describe a real-time relationship of the optic nerve sheath with increased intracranial pressure in children.
Caroline Driessen; Marie-Lise C van Veelen; Maarten Lequin; Koen F M Joosten; Irene M J Mathijssen
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Plastic and reconstructive surgery     Volume:  130     ISSN:  1529-4242     ISO Abbreviation:  Plast. Reconstr. Surg.     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-29     Completed Date:  2012-12-20     Revised Date:  2014-10-13    
Medline Journal Info:
Nlm Unique ID:  1306050     Medline TA:  Plast Reconstr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  448e-51e     Citation Subset:  AIM; IM    
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MeSH Terms
Child, Preschool
Craniosynostoses / complications,  surgery*,  ultrasonography*
Intracranial Hypertension / etiology,  prevention & control*,  ultrasonography*
Intracranial Pressure
Monitoring, Physiologic / methods
Myelin Sheath / ultrasonography*
Optic Nerve / ultrasonography*
Pilot Projects
Comment In:
Plast Reconstr Surg. 2012 Sep;130(3):452e-4e   [PMID:  22929270 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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