Document Detail

Nocturnal oxygen desaturation in patients with congestive heart failure.
MedLine Citation:
PMID:  11148986     Owner:  NLM     Status:  MEDLINE    
The aim of our study was to evaluate the modifications of the respiratory pattern during sleeping in patients with congestive heart failure (CHF) by a simple pulse-oxymetry. We studied 10 subjects (8M/2F), mean age 71.4 +/- 12.4 yrs, admitted to sub-intensive cardiological therapy unit, with diagnosis of CHF due to left ventricular insufficiency by ischemic, hypertensive or idiopathic cardiopathy, when in a stable clinical condition. All patients presented arterial blood gas values within normal limits. The ejection fraction of left ventricle showed a mean value of 30.4 +/- 8.2% (range 20%-45%). Nocturnal pulse-oxymetry was performed by pulse-oxymeter (PULSOX 7 Minolta) provided with a digital probe at a sliding speed 24 cm/h. Our data showed that all patients presented nocturnal desaturation episodes (mean oxygen desaturation index 15.7 +/- 18.4). In two patients, we found an "Overlap Syndrome" (obstructive sleep apnoea in presence of cardiopathy). In other patients pulse-oxymetry showed a typical sequence of "fall-rise" basal O2 saturation lasting from 36 to 72 seconds, collected in "wave trains" which were present from 14% to 70% of total sleep time compatible with periodic breathing. In conclusion, our study shows that patients affected by CHF, even if in stable condition and with a PaO2, within normal values, present more or less severe disturbances of nocturnal SaO2, with periodic and regular sequences of SaO2 fall-rise that may be referred to ventilatory troubles such as periodic breathing or Cheyne-Stokes breathing. In these patients the pulse-oxymetry may be considered an efficacious, simple, cheap and well tolerated method.
O Resta; M P Foschino-Barbaro; P G Bonfitto; S Talamo; M C Nocerino; A Stefà no; G Biasco
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bollettino della Società italiana di biologia sperimentale     Volume:  75     ISSN:  0037-8771     ISO Abbreviation:  Boll. Soc. Ital. Biol. Sper.     Publication Date:    1999 May-Jun
Date Detail:
Created Date:  2001-01-08     Completed Date:  2001-01-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7506962     Medline TA:  Boll Soc Ital Biol Sper     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  31-8     Citation Subset:  IM    
Department of Clinical Methodology and Medical Surgery Technology, S. Michele in Laureto Hospital, Putignano, Bari.
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MeSH Terms
Anoxia / etiology,  metabolism*,  physiopathology
Heart Failure / complications,  metabolism*,  physiopathology
Oximetry / methods
Oxygen / metabolism*
Parasomnias / etiology,  metabolism*,  physiopathology
Reg. No./Substance:

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