Document Detail

Nocturnal oxygen desaturation as a predictive risk factor for coronary restenosis after coronary intervention.
MedLine Citation:
PMID:  16247205     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Sleep-disordered breathing may affect coronary artery disease, so patients treated by percutaneous transluminal coronary angioplasty were studied to investigate the relationship between nocturnal oxygen desaturation (NOD) and the loss index. METHODS AND RESULTS: The nocturnal oxygen desaturation index (ODI) was determined by means of a pulse oximeter in 35 patients with coronary artery disease treated by stent placement. The patients were divided into 3 groups according to ODI: <5 events/h (group N, n=6), between 5 and 14 events/h (group A, n=19), and >or=15 events/h (group B, n=10). The relationship between the ODI and loss index was examined in each group. The loss index, 0.27+/-0.23 in group N, 0.30+/-0.27 in group A, and 0.70+/-0.32 in group B, differed significantly between groups N and B (p=0.007). In all patients, the loss index showed a significant positive correlation with the ODI (R=0.585, p=0.002). CONCLUSIONS: These findings suggest that NOD may be an important contributor to coronary restenosis in patients treated with stent placement.
Motonori Hayashi; Keisaku Fujimoto; Kazutoshi Urushibata; Hiroshi Imamura; Osamu Kinoshita; Keishi Kubo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  69     ISSN:  1346-9843     ISO Abbreviation:  Circ. J.     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-10-25     Completed Date:  2006-03-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1320-6     Citation Subset:  IM    
The First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
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MeSH Terms
Angioplasty, Balloon*
Blood Gas Monitoring, Transcutaneous
Case-Control Studies
Coronary Artery Disease / blood,  complications,  therapy*
Coronary Restenosis / blood*,  etiology
Middle Aged
Oxygen / blood*
Predictive Value of Tests
Risk Factors
Sleep Disorders / blood*,  etiology
Reg. No./Substance:

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