Document Detail


Nocturia and overnight polysomnography in Parkinson disease.
MedLine Citation:
PMID:  23359220     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: Characterize clinical factors related to nocturia and sleep disruption in Parkinson disease (PD) using polysomnography (PSG).
METHODS: Sixty-three PD patients were recruited regardless of sleep or voiding complaints from a university-based movement disorders clinic for a 48 hr inpatient PSG protocol. Nocturia frequency and bother related to urinary symptoms were assessed using the International Prostate Symptom Score (IPSS) and were corroborated by measurements of PSG-defined sleep made immediately preceding and subsequent to each in-lab voiding episode. PSG measures included whole-night total sleep time (TST), sleep efficiency (SE), apnea/hypopnea index (AHI), and time to PSG-defined sleep following nocturia episodes. Differences between groups were assessed using Mantel-Haenszel chi-square, t-tests, or Wilcoxon signed rank tests. Linear regression was used to assess factors associated with reported nocturia frequency.
RESULTS: Sixty patients completed the IPSS. Thirty-seven (61%) reported at least two nocturia episodes nightly; those individuals demonstrated lower PSG-defined SE (P = 0.01) and TST (P = 0.02) than patients with 0-1 episodes. Participants reporting 2-3 episodes of nocturia with high bother on the IPSS (n = 12) demonstrated lower whole-night TST (280.5 ± 116.1 min vs. 372.5 ± 58.7 min, P = 0.03) and worse SE (59.2 ± 22.7% vs. 75.9 ± 11.2%, P = 0.04) when compared to participants with 2-3 episodes of nocturia with low bother (n = 13).
CONCLUSIONS: These results verify objectively that PD patients with nocturia have poor sleep. Furthermore, among individuals with comparable levels of reported nocturia, higher bother is associated with poorer sleep as defined on PSG. Neurourol. Urodynam. Published 2013. This article is a U.S. Government work and is in the public domain in the USA.
Authors:
Camille P Vaughan; Jorge L Juncos; Lynn Marie Trotti; Theodore M Johnson; Donald L Bliwise
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2013-01-28
Journal Detail:
Title:  Neurourology and urodynamics     Volume:  32     ISSN:  1520-6777     ISO Abbreviation:  Neurourol. Urodyn.     Publication Date:  2013 Nov 
Date Detail:
Created Date:  2013-10-24     Completed Date:  2014-06-20     Revised Date:  2014-11-04    
Medline Journal Info:
Nlm Unique ID:  8303326     Medline TA:  Neurourol Urodyn     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1080-5     Citation Subset:  IM    
Copyright Information:
Published 2013. This article is a U.S. Government work and is in the public domain in the USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Female
Humans
Male
Middle Aged
Nocturia / complications*,  physiopathology
Parkinson Disease / complications*,  physiopathology
Polysomnography
Quality of Life
Sleep / physiology*
Grant Support
ID/Acronym/Agency:
KL2 RR025009/RR/NCRR NIH HHS; KL2 RR025009/RR/NCRR NIH HHS; R01 NS-050595/NS/NINDS NIH HHS; R01 NS050595/NS/NINDS NIH HHS; UL1 RR025008/RR/NCRR NIH HHS; UL1 RR025008/RR/NCRR NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Move to Improve: How Knee Osteoarthritis Patients Can Use Exercise to Enhance Quality of Life.
Next Document:  Influence of array interspacing on the force required for successful microneedle skin penetration: T...