| Nocardial infection in Crete, Greece: review of fifteen cases from 2003 to 2007. | |
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MedLine Citation:
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PMID: 19101858 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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During a 5-y period (2003 - 2007), nocardial infections were diagnosed in 15 patients admitted to the University Hospital of Heraklion, Crete, Greece. Nine patients (60%) had 1 or more underlying conditions predisposing to nocardiosis. The skin was involved in 10 cases, followed by the lung in 4. One patient had disseminated disease. Five different species were identified: N. brasiliensis (n =7), N. otitidiscaviarum (n=4), N. abscessus (n=2), N. transvalensis (n=1), and N. farcinica (n=1). The most common species was N. brasiliensis. All isolates were sensitive to linezolid, moxifloxacin, and tigecycline, and 80% of them to trimethoprim-sulfamethoxazole. Antibiotics were given to all 15 patients. A clinical response was observed in 14 of them, while 1 died of nocardiosis. Nocardiosis is a rare but sometimes life-threatening infection, complicating immunosuppression. Early diagnosis and timely administration of appropriate treatment result in a favourable outcome. |
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Authors:
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Sofia Maraki; Efstathia Scoulica; Eleni Nioti; Yannis Tselentis |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Scandinavian journal of infectious diseases Volume: 41 ISSN: 0036-5548 ISO Abbreviation: Scand. J. Infect. Dis. Publication Date: 2009 |
Date Detail:
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Created Date: 2009-01-13 Completed Date: 2009-04-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0215333 Medline TA: Scand J Infect Dis Country: Sweden |
Other Details:
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Languages: eng Pagination: 122-7 Citation Subset: IM |
Affiliation:
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Department of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine, University Hospital of Heraklion, Heraklion, Crete, Greece. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Anti-Bacterial Agents / therapeutic use Female Greece / epidemiology Humans Male Microbial Sensitivity Tests Middle Aged Nocardia / drug effects, genetics, isolation & purification* Nocardia Infections / diagnosis*, drug therapy, epidemiology*, microbiology Risk Factors Trimethoprim-Sulfamethoxazole Combination / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 8064-90-2/Trimethoprim-Sulfamethoxazole Combination |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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