Document Detail


Nocardia brasiliensis infection seen on grafted skin of the dorsum of a foot.
MedLine Citation:
PMID:  11479535     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
For the past 4 years a 23 y-old female has noticed erythema on the dorsum of the right foot, where skin was grafted due to a traffic accident 20 years ago. She visited the Department of Dermatology of Gifu Prefectural Hospital on Oct. 19, 1998; her general health was good. Physical examination disclosed a swelling with erythema, papules and pustules on the dorsum of the right foot. The results of routine laboratory investigations were within normal limits except for the white blood cell count (11,300/mm(3)), blood sediment rate (25 mm/hrs), C reactive protein (1.21) and rheumatoid factor (x 16.6). Several yellowish and verrucous or wrinkled colonies were grown on Sabourauds agar culture from the biopsied specimen of the foot. Histopathological features showed epidermal hyperplasia with elongation of rete ridges and granulomatous changes in the dermis; many mononuclear and giant cells were present, and several positive fine filamentous and irregularly branching structures with PAS and Grocott stains were seen in the granulomatous nests. Both clinical and histopathological features led to speculation of Nocardia infection, and Nocardia brasiliensis was determined. The patient was treated by surgical total resection including the grafted skin. Although a soybean-sized nodule was seen on the border of the skin-graft of the foot three months later, there was no recurrence after the local resection.
Authors:
M Maeda; M Sato; Y Tozaki; Y Okumura; Y Mikami
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology     Volume:  42     ISSN:  0916-4804     ISO Abbreviation:  Nihon Ishinkin Gakkai Zasshi     Publication Date:  2001  
Date Detail:
Created Date:  2001-07-31     Completed Date:  2001-11-01     Revised Date:  2011-06-24    
Medline Journal Info:
Nlm Unique ID:  9425640     Medline TA:  Nihon Ishinkin Gakkai Zasshi     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  137-42     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Prefectural Gifu Hospital, 4-6-1 Noishiki, Gifu City, 500-8717, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Foot / surgery
Foot Dermatoses / microbiology*,  pathology
Humans
Nocardia Infections / microbiology*,  pathology
Postoperative Complications
Skin Transplantation*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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