| Nocardia asteroides isolated from three patients with cystic fibrosis. | |
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MedLine Citation:
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PMID: 11957029 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Over a 7-year period, three patients with cystic fibrosis had multiple sputum specimens that were smear- and culture-positive for Nocardia asteroides. Two of the patients had received long-term, low-dose inhalational corticosteroid therapy. Although all three patients were treated with cotrimoxazole, resulting in eradication of the organism from the sputum, there was no change in their clinical state, radiological findings, or pulmonary function. The isolation of Nocardia asteroides from the respiratory tract of cystic fibrosis patients is an unusual finding. Its presence does not necessarily imply disease, and in these three cases, it most likely represented colonisation. The clinical significance of Nocardia spp. isolated from the respiratory tract of cystic fibrosis patients needs to be considered in the context of the individual clinical picture. |
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Authors:
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R Lumb; H Greville; J Martin; N Sangster; M Holmes |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2002-03-20 |
Journal Detail:
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Title: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology Volume: 21 ISSN: 0934-9723 ISO Abbreviation: Eur. J. Clin. Microbiol. Infect. Dis. Publication Date: 2002 Mar |
Date Detail:
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Created Date: 2002-04-16 Completed Date: 2002-05-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8804297 Medline TA: Eur J Clin Microbiol Infect Dis Country: Germany |
Other Details:
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Languages: eng Pagination: 230-3 Citation Subset: IM |
Affiliation:
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Infectious Diseases Laboratories, Institute of Medical and Veterinary Science, PO Box 14, Rundle Mall, Adelaide, South Australia 5001, Australia. richard.lumb@imvs.sa.gov.au |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adrenal Cortex Hormones / adverse effects Adult Anti-Bacterial Agents / therapeutic use Carrier State / microbiology* Cystic Fibrosis / complications*, microbiology* Female Humans Immunosuppressive Agents / adverse effects Male Nocardia Infections / complications*, drug therapy, microbiology* Nocardia asteroides / isolation & purification* Trimethoprim-Sulfamethoxazole Combination / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Anti-Bacterial Agents; 0/Immunosuppressive Agents; 8064-90-2/Trimethoprim-Sulfamethoxazole Combination |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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