Document Detail


No skeletal dysplasia in the nariokotome boy KNM-WT 15000 (homo erectus)-A reassessment of congenital pathologies of the vertebral column.
MedLine Citation:
PMID:  23283736     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The Nariokotome boy skeleton KNM-WT 15000 is the most complete Homo erectus fossil and therefore is key for understanding human evolution. Nevertheless, since Latimer and Ohman (2001) reported on severe congenital pathology in KNM-WT 15000, it is questionable whether this skeleton can still be used as reference for Homo erectus skeletal biology. The asserted pathologies include platyspondylic and diminutive vertebrae implying a disproportionately short stature; spina bifida; condylus tertius; spinal stenosis; and scoliosis. Based on this symptom complex, the differential diagnosis of spondyloepiphyseal dysplasia tarda, an extremely rare form of skeletal dysplasia, has been proposed. Yet, our reanalysis of these pathologies shows that the shape of the KNM-WT 15000 vertebrae matches that of normal modern human adolescents. The vertebrae are not abnormally flat, show no endplate irregularities, and thus are not platyspondylic. As this is the hallmark of spondyloepiphyseal dysplasia tarda and related forms of skeletal dysplasia, the absence of platyspondyly refutes axial dysplasia and disproportionate dwarfism. Furthermore, we neither found evidence for spina bifida occulta nor manifesta, whereas the condylus tertius, a developmental anomaly of the cranial base, is not related to skeletal dysplasias. Other fossils indicate that the relatively small size of the vertebrae and the narrow spinal canal are characteristics of early hominins rather than congenital pathologies. Except for the recently described signs of traumatic lumbar disc herniation, the Nariokotome boy fossil therefore seems to belong to a normal Homo erectus youth without pathologies of the axial skeleton. Am J Phys Anthropol, 2013. © 2013 Wiley Periodicals, Inc.
Authors:
Regula Schiess; Martin Haeusler
Related Documents :
23393626 - Littoral cell angioma of spleen: an uncommon presentation of a rare neoplasm.
16730126 - Diagnosis of bovine neosporosis.
24040546 - Vats left upper lobectomy.
23763806 - Serous cystadenocarcinoma of pancreas.
22351866 - Narrow-band imaging: a novel screening tool for early nasopharyngeal carcinoma.
7738656 - Diffuse renal retention on bone scintigraphy in localized clear-cell renal epithelial n...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-3
Journal Detail:
Title:  American journal of physical anthropology     Volume:  -     ISSN:  1096-8644     ISO Abbreviation:  Am. J. Phys. Anthropol.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400654     Medline TA:  Am J Phys Anthropol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Wiley Periodicals, Inc.
Affiliation:
Anthropological Institute and Museum, University of Zuerich, Winterthurerstrasse 190, 8057 Zuerich, Switzerland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Mycobacterium avium subspecies impair dendritic cell maturation.
Next Document:  LMP gene promoter hypermethylation is a mechanism for its down regulation in Kazak's esophageal squa...