Document Detail


No relation between vitamin D status and physical performance in the oldest old: results from the Belfrail study.
MedLine Citation:
PMID:  23360776     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: vitamin D deficiency is a well-known cause of bone loss and fractures but its association, especially among the oldest old, with muscle weakness is less obvious. OBJECTIVE: to investigate the relationship between 25-hydroxyvitamin D (25-OHD) and muscle performance in persons aged 80 years and older. METHODS: baseline results of the Belfrail study, a prospective, population-based cohort study were used to study balance, grip strength and gait speed in relation to 25-OHD serum levels in 367 subjects. RESULTS: a sufficient 25-OHD serum level of 30 ng/ml or more was found in 12.8% of the population. The prevalence of vitamin deficiency (20-29 ng/ml), insufficiency (10-19 ng/ml) and severe insufficiency (<10 ng/ml) was 21.5, 33 and 32.7%, respectively. No significant relation between balance, gait speed and grip strength, and serum 25-OHD was detected neither in bivariate analysis nor after adjustment for age, gender, level of education, institutionalisation, smoking status, body mass index, co-morbidity, level of activity, season, CRP, renal function, serum calcium parathyroid hormone levels, vitamin D intake and use of loop or thiazide diuretics. CONCLUSION: in this cohort of octogenarians vitamin D deficiency was highly prevalent. We could not confirm the findings of previous studies showing an association between serum 25-OHD and physical performance in elderly.
Authors:
Catharina Matheï; Gijs Van Pottelbergh; Bert Vaes; Wim Adriaensen; Didier Gruson; Jean-Marie Degryse
Related Documents :
22991166 - Plasma and urinary levels of dermatan sulfate and heparan sulfate derived disaccharides...
23985836 - A longitudinal study on α-synuclein in blood plasma as a biomarker for parkinson's dis...
24612806 - Short communication: timing of first milking affects serotonin (5-ht) concentrations.
22983646 - Sequential monitoring of serum il-6, tnf-α, and ifn-γ levels in a caebv patient treat...
6187146 - Treatment of sepsis in the surgical patient evaluated by means of chromogenic peptide s...
6473616 - The dependence of the clonidine growth hormone test on alcohol drinking habits and the ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-29
Journal Detail:
Title:  Age and ageing     Volume:  -     ISSN:  1468-2834     ISO Abbreviation:  Age Ageing     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375655     Medline TA:  Age Ageing     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of General Practice, KU Leuven, Leuven, Belgium.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Comparison of the therapeutic effects of human and mouse adipose-derived stem cells in a murine mode...
Next Document:  The role of contractile unit reorganization in force generation in airway smooth muscle.