| No-reflow following dilatation of a coronary lesion with a large lipid core. | |
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MedLine Citation:
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PMID: 12135142 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Radiolucent findings of coronary angiogram are believed to usually represent intracoronary thrombus, but in the present case, were atheromatous plaque with a large lipid core. A 62-year-old man who suffered from an inferior acute myocardial infarction was admitted to hospital 6 h after onset. The first cine angiograms showed TIMI-1 flow in the distal-portion of the right coronary artery, so thrombectomy was initially carried out and TIMI-2 flow achieved. However, the radiolucent lesion did not disappear and so adjunctive mechanical dilatation of the lesion was prformed, which resulted in 'no-reflow' (TIMI-0). Finally, aspiration of the material from the stagnated lesion was attempted and immediately obtained TIMI-3 flow. The retrieved materials were macrophages (foam cells) and many cholesterol crystals, both of which are considered to be atheromatous gruel. Therefore, the sudden flow reduction following percutaneous transluminal coronary angioplasty was caused by mechanical disruption of an atheromatous plaque with a large lipid core. |
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Authors:
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Jun-ichi Kotani; Shinsuke Nanto; Masafumi Kitakaze; Tomoki Ohara; Takakazu Morozumi; Tetsuya Watanabe; Masashi Fujita; Masatsugu Hori; Seiki Nagata |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 66 ISSN: 1346-9843 ISO Abbreviation: Circ. J. Publication Date: 2002 Jul |
Date Detail:
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Created Date: 2002-07-23 Completed Date: 2003-06-03 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
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Languages: eng Pagination: 702-4 Citation Subset: IM |
Affiliation:
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Cardiovascular Division, Kansai Rosai Hospital, Amagasaki, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Transluminal, Percutaneous Coronary Atherectomy, Coronary* Blood Flow Velocity* Cholesterol Coronary Artery Disease / metabolism, pathology*, physiopathology Humans Lipids* Macrophages Male Middle Aged Myocardial Infarction / etiology |
| Chemical | |
Reg. No./Substance:
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0/Lipids; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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