Document Detail

No parallel between the biochemical course of acute pancreatitis and morphologic findings.
MedLine Citation:
PMID:  8190726     Owner:  NLM     Status:  MEDLINE    
The clinical, biochemical (serum enzymes), and morphologic course of acute pancreatitis was studied in 83 consecutive patients from time of admission until 3 months after discharge. At discharge, all 75 surviving patients had no more symptoms of acute pancreatitis, even though amylase (in 11%) and lipase (in 25%) were still elevated, computed tomography (CT) findings still abnormal (in 81%), and necrosis amounting up to 50% of the gland still present (in 24%). There was no significant correlation between serum enzymes and CT findings at discharge. Three months later, with the exception of one patient with an acute relapse of the disease, all followed-up patients were free of symptoms and had normal serum amylase, whereas lipase was still elevated in 10%, and CT findings abnormal in 23%. Subsiding symptoms provided a more accurate picture of the patients' recovery than the biochemical markers, and even more so that the morphologic findings.
P G Lankisch; M Haseloff; R Becher
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Pancreas     Volume:  9     ISSN:  0885-3177     ISO Abbreviation:  Pancreas     Publication Date:  1994 Mar 
Date Detail:
Created Date:  1994-06-21     Completed Date:  1994-06-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8608542     Medline TA:  Pancreas     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  240-3     Citation Subset:  IM    
Department of Internal Medicine, Municipal Hospital of Lüneburg, Germany.
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MeSH Terms
Acute Disease
Aged, 80 and over
Follow-Up Studies
Middle Aged
Pancreatitis / enzymology*,  pathology*,  radiography
Prospective Studies
Tomography, X-Ray Computed

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