| No link between rosacea and Propionibacterium acnes. | |
| | |
MedLine Citation:
|
PMID: 23009116 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Rosacea is a common skin disease in adults affecting mainly the facial skin. Although inflammation appears to play a pathogenic role in rosacea, initiating factors are largely unknown. Microbial involvement in the development of rosacea has been suggested previously. We aimed to visualize Propionibacterium acnes in the skin compartments of rosacea patients. Facial skin biopsies from 82 rosacea patients and 25 controls were stained with a P. acnes-specific monoclonal antibody (QUBPa3). Seven of 82 patients (8.5%) tested positive for P. acnes which was present either as a biofilm (57% of positive) or a microcolony (43%) in colonized patients. Our results suggest that P. acnes does not play a major role in the pathogenesis of rosacea. |
| | |
Authors:
|
Anika C Jahns; Bertil Lundskog; Ida Dahlberg; Natalia Curiche Tamayo; Andrew McDowell; Sheila Patrick; Oleg A Alexeyev |
Related Documents
:
|
23640556 - Cytogenetic profile of aplastic anaemia in indian children. 23565426 - Selenium and the thyroid: a close-knit connection. 767366 - The effect of systematic plaque control on bone regeneration in infrabony pockets. 23418296 - Meniere's disease: a reappraisal supported by a variable latency of symptoms and the mr... 8180906 - Dysphagia in ambulant patients with parkinson's disease: common, not dangerous. 1737246 - Agreement between clinical methods of measurement of urinary frequency and functional b... |
Publication Detail:
|
Type: Journal Article Date: 2012-05-18 |
Journal Detail:
|
Title: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica Volume: 120 ISSN: 1600-0463 ISO Abbreviation: APMIS Publication Date: 2012 Nov |
Date Detail:
|
Created Date: 2012-09-26 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8803400 Medline TA: APMIS Country: Denmark |
Other Details:
|
Languages: eng Pagination: 922-5 Citation Subset: IM |
Copyright Information:
|
© 2012 The Authors APMIS © 2012 APMIS. |
Affiliation:
|
Department of Medical Biosciences/Pathology, Umeå University, Umeå, Sweden. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The use of sequential organ failure assessment parameters in an awake porcine model of severe Staphy...
Next Document: Antibiotic resistance and molecular epidemiology of the beta-lactamase-producing Haemophilus influen...