Document Detail

No incremental clinical information of NT Pro BNP at peak exercise over resting levels in patients with impaired left ventricular function.
MedLine Citation:
PMID:  17145088     Owner:  NLM     Status:  MEDLINE    
There is an increasing tension to use NT Pro BNP blood levels at peak exercise testing. Their possible superiority over resting levels in congestive heart failure or factors associated with their increase have not been adequately studied. We studied 65 patients, 51 males and 14 females with impaired left ventricular function. Mean left ventricular ejection fraction (LVEF) was 35+/-9%. Our findings suggest that in patients with heart failure NT Pro BNP plasma levels at peak exercise do not provide incremental clinical information over resting levels. Baseline NT Pro BNP alone can provide sufficient clinical information.
M S Kallistratos; A Dritsas; I D Laoutaris; D V Cokkinos
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Publication Detail:
Type:  Comparative Study; Letter     Date:  2006-12-04
Journal Detail:
Title:  International journal of cardiology     Volume:  121     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-10-23     Completed Date:  2007-12-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  221-3     Citation Subset:  IM    
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MeSH Terms
Biological Markers / blood
Exercise Test* / methods
Natriuretic Peptide, Brain / blood*
Peptide Fragments / blood*
Rest / physiology*
Ventricular Dysfunction, Left / blood*,  diagnosis,  physiopathology
Reg. No./Substance:
0/Biological Markers; 0/Peptide Fragments; 0/pro-brain natriuretic peptide (1-76); 114471-18-0/Natriuretic Peptide, Brain

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