Document Detail


No effect of menstrual cycle phase on lactate threshold.
MedLine Citation:
PMID:  14600163     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
No previous exercise studies in women have assessed the effects of the normal menstrual cycle on the lactate threshold (LT) measured during a graded, maximal exercise test. This is relevant to our understanding of exercise training and metabolism in eumenorrheic women. The present study, therefore, examined the effect of menstrual cycle phase on the LT. Eight moderately active, eumenorrheic women performed three maximal exercise tests with simultaneous determination of LT. Tests were performed in the early follicular (low estrogen and progesterone), midfollicular (elevated estrogen and low progesterone), and midluteal (elevated estrogen and progesterone) phases of the menstrual cycle. No significant differences were observed in LT measured across phases of the menstrual cycle whether data were expressed in absolute terms (1299 +/- 70, 1364 +/- 80, and 1382 +/- 71 ml O(2)/min, respectively) or relative to maximal oxygen uptake (V(o2 max); 52.1 +/- 1.7, 54.7 +/- 1.7, and 55.7 +/- 1.6%, respectively). In addition, there were no significant cycle phase differences in V(o2 max), maximal heart rate, heart rate at LT, or final lactate concentration. With data combined across all phases of the menstrual cycle, there was a significant correlation between the LT and the epinephrine breakpoint (r = 0.91, P < 0.0002) and norepinephrine breakpoint (r = 0.94, P < 0.0001). For epinephrine only, there was close correspondence between the epinephrine breakpoint (ml O(2)/min) and the LT. In conclusion, LT as well as V(o2 max) and other measures of cardiorespiratory fitness are not significantly affected by the changing sex steroid levels observed across the normal menstrual cycle. Data suggest that the onset of the steep increase in epinephrine determines the LT during graded exercise.
Authors:
Teresa M Dean; Leigh Perreault; Robert S Mazzeo; Tracy J Horton
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  95     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-11-05     Completed Date:  2004-07-06     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2537-43     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anaerobic Threshold / physiology
Catecholamines / metabolism
Diet
Exercise / physiology*
Exercise Test
Female
Follicular Phase / physiology
Heart Rate / physiology
Humans
Lactic Acid / blood*
Luteal Phase / physiology
Menstrual Cycle / metabolism,  physiology*
Oxygen Consumption / physiology
Spectrophotometry, Ultraviolet
Grant Support
ID/Acronym/Agency:
DK-48520/DK/NIDDK NIH HHS; HL-04226/HL/NHLBI NIH HHS; M01 RR-00051/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Catecholamines; 50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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