Document Detail


No effect of hyperbaric oxygen on methionine synthetase activity in rats.
MedLine Citation:
PMID:  6638553     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nitrous oxide is the only anesthetic gas or vapor known to inactivate the vitamin B12 cofactor of the enzyme methionine synthetase. However, there are conflicting reports on whether oxygen at one atmosphere has any effect. The authors found that the hepatic methionine synthetase activity of Sprague-Dawley rats was unchanged after 4 h exposure to two atmospheres of oxygen.
Authors:
N M Sharer; S J Monk; J F Nunn
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anesthesiology     Volume:  59     ISSN:  0003-3022     ISO Abbreviation:  Anesthesiology     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1983-12-17     Completed Date:  1983-12-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1300217     Medline TA:  Anesthesiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  440-1     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase / metabolism*
Animals
Hyperbaric Oxygenation*
Liver / enzymology
Male
Methyltransferases / metabolism*
Rats
Rats, Inbred Strains
Chemical
Reg. No./Substance:
EC 2.1.1.-/Methyltransferases; EC 2.1.1.13/5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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