| No decrease of HDL cholesterol after 6 days of low fat and high carbohydrate diets in a young Chinese Han population. | |
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MedLine Citation:
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PMID: 18798502 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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More studies are needed on the hypertriacylglycerolemic effects of low fat and high carbohydrate (LF-HC) diet in young population, especially Chinese who generally have a diet containing lower fat and higher carbohydrate. To test them in a young Chinese Han population, 56 healthy subjects (22.89 +/- 1.80) years were given regular diet of 31% fat and 54% carbohydrate for 7 days, followed by LF-HC diet of 15% fat and 70% carbohydrate for 6 days, without total energy restriction. After the LF-HC diet, the male experienced an increase of high density lipoprotein (HDL) cholesterol and decreases of weight, body mass index (BMI), total cholesterol (TC), and LDL (low density lipoprotein) cholesterol (P < 0.05). The female experienced increased serum triacylglycerol and insulin, and decreased TC and LDL cholesterol (P < 0.05). When BMI was taken into account, all the subjects with low, medium, or high BMI experienced decreases of TC and LDL cholesterol although some changes were not significant. No significant decrease of HDL cholesterol was found, while significantly increased HDL cholesterol and apolipoprotein A-I (apo A-I) were found in the male subjects with low or high BMI (P < 0.05). Significant increase of triacylglycerol was observed only in the female subjects with low or medium BMI. In conclusion, subjects with different BMI and gender have different triacylglycerol and HDL cholesterol responses to LF-HC diets, and significant increase of HDL cholesterol and apolipoprotein A- I were observed in some young male subjects. |
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Authors:
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Zheng-ke Li; Hui Tang; Ren-rong Gong; Jia Lin; Chan-fen Gan; Xin Huang; Rong-hui Li; Ding-zhi Fang |
Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition Volume: 39 ISSN: 1672-173X ISO Abbreviation: Sichuan Da Xue Xue Bao Yi Xue Ban Publication Date: 2008 Jul |
Date Detail:
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Created Date: 2008-09-18 Completed Date: 2009-02-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101162609 Medline TA: Sichuan Da Xue Xue Bao Yi Xue Ban Country: China |
Other Details:
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Languages: eng Pagination: 595-600 Citation Subset: IM |
Affiliation:
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Department of Biochemistry and Molecular Biology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Asian Continental Ancestry Group Body Mass Index China Cholesterol, HDL / blood* Diet, Fat-Restricted* Dietary Carbohydrates / administration & dosage* Dietary Fats / administration & dosage* Female Humans Male Sex Factors Triglycerides / blood Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 0/Dietary Carbohydrates; 0/Dietary Fats; 0/Triglycerides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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