Document Detail


No benefit from conservative management in nulliparous women with premature rupture of the membranes (PROM) at term. A randomized study.
MedLine Citation:
PMID:  1785268     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To compare maternal and fetal outcome in pregnancies with premature rupture of the membranes (PROM) at term with either early induction of labor or conservative management awaiting spontaneous labor. DESIGN: A prospective randomized trial. SETTING: The University Hospital of Lund, Sweden. SUBJECTS: Altogether 369 women with singleton pregnancy, cephalic presentation, gestational duration 36-41 weeks, were randomized either to induction of labor (n = 139) or conservative management up to 3 days (n = 138). Those eligible but not participating in the study totalled 92. MAIN OBSTETRIC MEASURES: Obstetric intervention rate (cesarean section or instrumental delivery) and short-term neonatal morbidity. RESULTS: No difference was found in the rate of obstetric intervention between the induction of labor group and the group with conservative management (12.2 vs. 18.8%; chi 2 = 2.3, p greater than 0.05). A slightly increased rate of neonatal infections was seen in the latter group (0.7 vs. 4.3%; chi 2 = 3.2, p less than 0.05). CONCLUSIONS: We found no benefit from conservative management for up to 3 days in women with PROM at term, compared with immediate induction of labor. There was no difference in the number of obstetric interventions during labor. The neonatal infectious morbidity was slightly higher in conservatively managed cases.
Authors:
H Rydhstr?m; I Ingemarsson
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  70     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  1991  
Date Detail:
Created Date:  1992-03-19     Completed Date:  1992-03-19     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  543-7     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University Hospital, Lund University, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Adult
Cesarean Section / statistics & numerical data*
Chorioamnionitis / prevention & control
Endometritis / epidemiology,  etiology
Female
Fetal Membranes, Premature Rupture / complications,  therapy*
Humans
Infant, Newborn
Infant, Newborn, Diseases / epidemiology,  etiology
Infection / epidemiology,  etiology
Labor, Induced / adverse effects
Parity
Pregnancy
Pregnancy Outcome / epidemiology*
Prospective Studies
Treatment Outcome
Comments/Corrections
Comment In:
Acta Obstet Gynecol Scand. 1992 Oct;71(7):570-2   [PMID:  1332381 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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