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No Thyroid Abnormalities in Patients Submitted to Cardiac Catheterization in the First Eighteen Months of Life.
MedLine Citation:
PMID:  22189459     Owner:  NLM     Status:  Publisher    
Background: No data are available about the risk of thyroid disturbance after exposure of low dose radiation due to the use of cardiac catheterization in the first years of life. Aim: To determine the risk of functional and morphological thyroid abnormalities in a homogeneous cohort of patients who underwent diagnostic low-dose radiation for heart catheterization during the first eighteen months of life. Subjects and Methods: Fifty five patients, submitted to cardiac catheterization during the first 18 months of life, underwent evaluation of the thyroid function and structure after a median period of 13 years since the first radiation exposure. Sixty-eight unexposed controls matched for age and sex, underwent the same protocol. Twenty-two patients were then re-evaluated after a median period of 22 years. Results Thyroid function resulted normal in both patients and controls. The prevalence of small thyroid nodules and inhomogeneous structures in ultrasound study was not augmented in irradiated patients compared to controls. No thyroid tumors or reduced thyroid volume were observed. Conclusions Neither functional nor morphological disorders of the thyroid gland were demonstrated after a period up to 24 years in patients exposed to diagnostic ionizing radiation for cardiac catheterization during the first eighteen months of life.
M Cappa; P Cambiaso; E Genovese; D Kiepe; M Colajacomo; S Giannico; G Giannone; R Guglielmi; L Papini; V Cannatà
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-21
Journal Detail:
Title:  Journal of endocrinological investigation     Volume:  -     ISSN:  1720-8386     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7806594     Medline TA:  J Endocrinol Invest     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department University-Hospital, Endocrinology Unit, Bambino Gesù Children's Hospital-Tor Vergata University, Rome, Italy.
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