| No Higher Risk of CRPS After External Fixation of Distal Radial Fractures - Subgroup Analysis Under Randomised Vitamin C Prophylaxis. | |
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MedLine Citation:
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PMID: 20309405 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Operative and conservative treatment of wrist fractures might lead to complex regional pain syndrome (CRPS) type I.In our multicenter dose response study in which patients with distal radial fractures were randomly allocated to placebo or vitamin C in a daily dose of 200mg, 500mg or 1500mg during 50 days, an operated subgroup was analyzed.48 (of 427) fractures) were operated (11.2%). Twenty-nine patients (60%) were treated with external fixation, 14 patients (29%) with K-wiring according to Kapandji and five patients (10%) with internal plate fixation. The 379 remaining patients were treated with a plaster.In the operated group of patients who received vitamin C no CRPS (0/37) was seen in comparison with one case of CRPS (Kapandji technique) in the operated group who received placebo (1/11 = 9%, p=.23). There was no CRPS after external fixation.In the conservatively treated group 17 cases of CRPS (17/379 = 4.5%) occurred in comparison with one in case of CRPS in the operated group (1/48 = 2.1%, p=.71).External fixation doesn't necessarily lead to a higher incidence of CRPS in distal radial fractures. Vitamin C may also play a role in this. This subgroup analysis in operated distal radial fractures showed no CRPS occurrence with vitamin C prophylaxis. |
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Authors:
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Paul E Zollinger; Robert W Kreis; Hub G van der Meulen; Maarten van der Elst; Roelf S Breederveld; Wim E Tuinebreijer |
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Publication Detail:
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Type: Journal Article Date: 2010-02-17 |
Journal Detail:
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Title: The open orthopaedics journal Volume: 4 ISSN: 1874-3250 ISO Abbreviation: Open Orthop J Publication Date: 2010 |
Date Detail:
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Created Date: 2010-03-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101480491 Medline TA: Open Orthop J Country: Netherlands |
Other Details:
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Languages: eng Pagination: 71-5 Citation Subset: - |
Affiliation:
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Department of Orthopaedic Surgery, Ziekenhuis Rivierenland, Pres. Kennedylaan 1, 4002 WP Tiel, The Netherlands. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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