| Nitrous oxide availability. | |
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MedLine Citation:
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PMID: 7381032 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nitrous oxide (N2O) is marketed as an inhalation anesthetic and as a food ingredient (e.g., whipping cream propellant). In the human, inhalation has been associated with "highs," peripheral nerve damage, mitotic poisoning of bone marrow, psychosis, and mental impairment. Exposure to hypoxemic mixtures has resulted in death. The commercial N2O sources specifically studied were aerosol whipping cream containers (three brands) and 6.5-cm cylinders, or chargers (two brands). The gas content and N2O concentrations of these devices were measured. The aerosol cans, when not shaken, will dispense at least 3 liters of 87 to 90% N2O. Charger misuse may occur when they are substituted for identically designed carbon dioxide (CO2) chargers of a seltzer bottle; 4.3 to 5.0 liters of 93 to 98% N2O is expelled at a controllable rate. The toxicity of these inexpensive N2O products, their high potential for misuse, and the absence of labeling (chargers) argue that their distribution be discontinued. |
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Authors:
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M J Murray; W J Murray |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical pharmacology Volume: 20 ISSN: 0091-2700 ISO Abbreviation: J Clin Pharmacol Publication Date: 1980 Apr |
Date Detail:
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Created Date: 1980-08-15 Completed Date: 1980-08-15 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0366372 Medline TA: J Clin Pharmacol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 202-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aerosols Drug Labeling Household Products Humans Nitrous Oxide / supply & distribution* Substance-Related Disorders / epidemiology* United States |
| Chemical | |
Reg. No./Substance:
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0/Aerosols; 10024-97-2/Nitrous Oxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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