| Nitrosamines and nitrosamides in the etiology of gastrointestinal cancer. | |
| | |
MedLine Citation:
|
PMID: 922686 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
It has been amply demonstrated that N-nitroso compounds are formed by interaction of nitrite with secondary and tertiary amino compounds, and that this reaction can occur in vivo as well as in food processed with nitrite. The favored site of reaction in vivo is the stomach. It is likely that N-nitroso compounds formed in this way, especially nitrosamides, could reach the colon and contribute to the induction of colon tumors. |
| | |
Authors:
|
W Lijinsky |
Related Documents
:
|
12693206 - Selective one-electron reduction of nitrosomonas europaea hydroxylamine oxidoreductase ... 19888966 - Nitrite, no and hypoxic vasodilation. 6277846 - Respiration-dependent proton translocation in nitrosomonas europaea and its apparent ab... 22000936 - Synthesis and biological assessment of diversely substituted furo[2,3-b]quinolin-4-amin... 22063956 - Irradiation effects on meat flavor: a review. 9354936 - Oxidants differentially regulate the heat shock response. |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Cancer Volume: 40 ISSN: 0008-543X ISO Abbreviation: Cancer Publication Date: 1977 Nov |
Date Detail:
|
Created Date: 1978-01-27 Completed Date: 1978-01-27 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0374236 Medline TA: Cancer Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 2446-9 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Amides
/
metabolism* Animals Carcinogens Colonic Neoplasms / chemically induced Cricetinae Gastrointestinal Neoplasms / chemically induced* Guinea Pigs Humans Nitrosamines / metabolism*, pharmacology Nitroso Compounds / metabolism* Rats |
| Chemical | |
Reg. No./Substance:
|
0/Amides; 0/Carcinogens; 0/Nitrosamines; 0/Nitroso Compounds |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The large bowel carcinogenic effects of hydrazines and related compounds occurring in nature and in ...
Next Document: Inhibition of carcinogenic effect of bracken fern (Pteridium aquilinum) by various chemicals.