Document Detail

Nitrosamine excretion in patients with continent ileal reservoirs for urinary diversion.
MedLine Citation:
PMID:  1552576     Owner:  NLM     Status:  MEDLINE    
Adenocarcinomas are a recognized complication following ureterosigmoidostomy for which the endogenous formation of N-nitroso compounds may be a risk factor. As an alternative means of urinary diversion, the continent ileal reservoir has recently been developed. Microbiological and chemical investigations on the urine of patients with an ileal reservoir showed the presence of bacteria, nitrate, nitrite and N-nitrosamines formed endogenously in the ileal pouch. The role of nitrosamines in carcinogenesis in these patients as a late stage complication resulting from the use of a continent ileal reservoir is discussed.
J Gröschel; G Riedasch; T Kälble; A R Tricker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of urology     Volume:  147     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1992 Apr 
Date Detail:
Created Date:  1992-04-29     Completed Date:  1992-04-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1013-6     Citation Subset:  AIM; IM    
Department of Urology, University of Heidelberg, Federal Republic of Germany.
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MeSH Terms
Bacteria / metabolism
Ileum / surgery*
Middle Aged
Nitrates / metabolism,  urine
Nitrites / metabolism,  urine
Nitrosamines / metabolism,  urine*
Urinary Reservoirs, Continent*
Urine / microbiology
Reg. No./Substance:
0/Nitrates; 0/Nitrites; 0/Nitrosamines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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