Document Detail

Nitrogen balance in older individuals in energy balance depends on timing of protein intake.
MedLine Citation:
PMID:  20622139     Owner:  NLM     Status:  MEDLINE    
To explore whether nitrogen retention can differ on an isonitrogenous diet by changing when protein is consumed, we performed a short-term study in older individuals (64.5 ± 2.0 years) performing daily exercise while in energy balance. Participants consumed an isonitrogenous-isocaloric diet with the timing of a protein or carbohydrate beverage after exercise (protein after exercise [PRO], carbohydrate after exercise [CHO]) versus earlier in the day. Three-day mean energy balance (PRO: 202 ± 36 kcal and CHO: 191 ± 44 kcal; p = .68) did not differ between trials, but 3-day mean nitrogen balance was significantly more positive in the PRO (1.2 ± 0.32 g N) trial than the CHO trial (0.8 ± 0.45 g N; p < .05). Older individuals were better able to maintain nitrogen balance by simply changing when a portion of an identical amount of daily protein was consumed.
Leora Y Jordan; Edward L Melanson; Christopher L Melby; Matthew S Hickey; Benjamin F Miller
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2010-07-09
Journal Detail:
Title:  The journals of gerontology. Series A, Biological sciences and medical sciences     Volume:  65     ISSN:  1758-535X     ISO Abbreviation:  J. Gerontol. A Biol. Sci. Med. Sci.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-13     Completed Date:  2010-10-01     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  9502837     Medline TA:  J Gerontol A Biol Sci Med Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1068-76     Citation Subset:  AIM; IM    
Department of Health and Exercise Science, Colorado State University, Fort Collins, CO 80523-1582, USA.
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MeSH Terms
Cross-Over Studies
Dietary Carbohydrates / pharmacology
Dietary Proteins / pharmacology*
Energy Metabolism / physiology*
Exercise / physiology
Middle Aged
Nitrogen / metabolism*
Nutritional Requirements
Time Factors
Grant Support
1UL1 RR025780/RR/NCRR NIH HHS; K01AG031829-01/AG/NIA NIH HHS
Reg. No./Substance:
0/Dietary Carbohydrates; 0/Dietary Proteins; 7727-37-9/Nitrogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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