| Nitroderm TTS band application for pain after hemorrhoidectomy. | |
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MedLine Citation:
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PMID: 11357030 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Anal sphincter spasm is believed to play an important role in pain after hemorrhoidectomy. We tested a different form of nitroglycerin: the Nitroderm TTS band. We investigated its efficacy on posthemorrhoidectomy pain and the relation between pain and anal resting pressure measured preoperatively and postoperatively. METHODS: Thirty-eight hemorrhoid patients were divided into two groups: those with high anal resting pressure were classified as group A (n = 24) and those with low anal resting pressure were classified as group B (n = 14). After hemorrhoidectomy, Nitroderm TTS bands were placed into the anal canal in half of the patients in groups A and B (groups A-1 and B-1) and not in the remaining half (groups A-2 and B-2). Anal resting pressure measurement was repeated at the first day and third month postoperatively. Postoperative pain was assessed by linear analog scale, and analgesic consumption was recorded. RESULTS: Preoperative anal resting pressure was 112.0 (range, 95-140) cm H2O in group A-1 and 110.6 (range, 96-138) cm H2O in group A-2. The difference was insignificant. However, on the first postoperative day, anal resting pressures were 88.7 (range, 75-115) and 110.9 (range, 92-135) cm H2O (P = 0.0001), and at the third month, they were 76.5 (range, 70-100) and 78.0 (range, 70-105) cm H2O, respectively (P = 0.690). Postoperative pain scores were significantly lower in group A-1 than group A-2 (P = 0.0001). In the low-pressure groups (B-1 and B-2), anal resting pressures before surgery, on the first postoperative day, and at the third month postoperatively were 70.4 (range, 56-76), 67.4 (range, 50-75), and 67.2 (range, 55-74) cm H2O in group B-1 and 69.8 (range, 58-76), 70.2 (range, 60-76), and 68.4 (range, 60-74) cm H2O in group B-2. The differences were insignificant (P > or = 0.660). The differences between pain scores in these groups were also insignificant (P > or = 0.160). CONCLUSION: Nitroderm TTS bands effectively reduced anal resting pressure and relieved pain in patients with high preoperative anal resting pressure. |
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Authors:
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A Coskun; S A Duzgun; A Uzunkoy; M Bozer; O Aslan; B Canbeyli |
Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Diseases of the colon and rectum Volume: 44 ISSN: 0012-3706 ISO Abbreviation: Dis. Colon Rectum Publication Date: 2001 May |
Date Detail:
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Created Date: 2001-05-17 Completed Date: 2001-06-07 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372764 Medline TA: Dis Colon Rectum Country: United States |
Other Details:
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Languages: eng Pagination: 680-5 Citation Subset: IM |
Affiliation:
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Harran University School of Medicine, Departments of General Surgery and Pharmacology, Sanliurfa, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Cutaneous Adult Aged Anal Canal / physiology, surgery Female Hemorrhoids / pathology, surgery* Humans Male Manometry Middle Aged Nitroglycerin / administration & dosage*, pharmacology Pain / drug therapy*, etiology Postoperative Complications / prevention & control Pressure Treatment Outcome Vasodilator Agents / administration & dosage*, pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Vasodilator Agents; 55-63-0/Nitroglycerin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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