Document Detail


Nitric oxide regulation of adult neurogenesis.
MedLine Citation:
PMID:  25189384     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The ubiquitous gaseous signaling molecule nitric oxide participates in the regulation of a variety of physiological and pathological processes, including adult neurogenesis. Adult neurogenesis, or the generation of new neurons in the adult brain, is a restricted event confined to areas with neurogenic capability. Although nitric oxide has been shown to mediate conflicting effects on adult neurogenesis, which may be partly explained by its unique characteristics, more studies are required in order to fully comprehend and appreciate the mechanisms involved. Neuropeptide Y, a neurotransmitter shown to be an important regulator of adult hippocampal neurogenesis, acts through intracellular nitric oxide to induce an increase in neural progenitor cell proliferation.
Authors:
William P Gray; Angela Cheung
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Vitamins and hormones     Volume:  96     ISSN:  0083-6729     ISO Abbreviation:  Vitam. Horm.     Publication Date:  2014  
Date Detail:
Created Date:  2014-09-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413601     Medline TA:  Vitam Horm     Country:  United States    
Other Details:
Languages:  eng     Pagination:  59-77     Citation Subset:  IM    
Copyright Information:
© 2014 Elsevier Inc. All rights reserved.
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