| Nitric oxide and its effects on the calcium transport systems in the myocardium. | |
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MedLine Citation:
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PMID: 9452943 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nitric oxide (NO) is an important modulator of many physiological processes, including myocardial contractile function. The understanding of how the production of NO in the myocardium is regulated in response to physiological stimuli and pathological processes is evolving rapidly. The main goal of this minireview is to summarize the current knowledge (i) about the enzymes that produce NO in the heart muscle, (ii) about the targets of myocardial NO that modulate calcium transport systems of the heart muscle cells, and (iii) about the role that NO-induced changes of calcium homeostasis play in the modulation of myocardial contractility. |
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Authors:
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A Zahradníková; O Krizanová |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: General physiology and biophysics Volume: 16 ISSN: 0231-5882 ISO Abbreviation: Gen. Physiol. Biophys. Publication Date: 1997 Sep |
Date Detail:
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Created Date: 1998-03-12 Completed Date: 1998-03-12 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8400604 Medline TA: Gen Physiol Biophys Country: SLOVAKIA |
Other Details:
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Languages: eng Pagination: 197-214 Citation Subset: IM |
Affiliation:
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Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences, Bratislava, Slovakia. umfgzahr@kramare.savba.sk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Biological Transport Calcium / metabolism* Humans Myocardial Contraction Myocardium / enzymology, metabolism* Nitric Oxide / physiology* Nitric Oxide Synthase / antagonists & inhibitors, metabolism |
| Chemical | |
Reg. No./Substance:
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10102-43-9/Nitric Oxide; 7440-70-2/Calcium; EC 1.14.13.39/Nitric Oxide Synthase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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