| Nitric oxide inhalation is useful in the management of right ventricular failure caused by myocardial infarction. | |
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MedLine Citation:
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PMID: 12072697 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To describe hemodynamic improvement in a patient treated with nitric oxide (NO) inhalation in the management of right ventricular failure caused by myocardial infarction. DESIGN: Case report. SETTING: An intensive care unit of a university hospital. PATIENT: A 66-yr-old man with severe right ventricular failure caused by acute myocardial infarction. INTERVENTIONS: Nitric oxide inhalation through a ventilator circuit. MEASUREMENTS AND MAIN RESULTS: The patient complained of chest pain. When myocardial infarction was diagnosed, he underwent percutaneous transluminal coronary angioplasty and percutaneous transluminal coronary recanalization, but they were not effective. We instituted intra-aortic balloon pumping and brought the patient to the intensive care unit (ICU). Even with high-dose inotropic support, his hemodynamics deteriorated gradually. On the patient's seventh day in the ICU, we started NO inhalation at 5-10 ppm in an attempt to relieve his right heart failure. Immediately after NO inhalation was started, his hemodynamics improved significantly, and we could wean the patient from intra-aortic balloon pumping. NO inhalation was continued for 9 days and was successfully discontinued without circulatory deterioration. He was discharged from our hospital uneventfully. CONCLUSION: Nitric oxide inhalation improved hemodynamics in our patient with right ventricular failure after myocardial infarction. Our report suggests that a clinical trial of NO treatment for severe right ventricular failure caused by myocardial infarction is warranted. |
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Authors:
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Yoshihito Fujita; Osamu Nishida; Kazuya Sobue; Hiroaki Ito; Nobuyoshi Kusama; Masaaki Inagaki; Hirotada Katsuya |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Critical care medicine Volume: 30 ISSN: 0090-3493 ISO Abbreviation: Crit. Care Med. Publication Date: 2002 Jun |
Date Detail:
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Created Date: 2002-06-19 Completed Date: 2002-07-10 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0355501 Medline TA: Crit Care Med Country: United States |
Other Details:
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Languages: eng Pagination: 1379-81 Citation Subset: AIM; IM |
Affiliation:
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Department of Anesthesiology and Resuscitology, Nagoya City University Medical School, Nagoya, Japan. yfujita@med.nagoya-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Inhalation Aged Angioplasty, Transluminal, Percutaneous Coronary Hemodynamics / drug effects* Humans Male Myocardial Infarction / complications*, therapy Nitric Oxide / administration & dosage, therapeutic use* Treatment Outcome Vasodilator Agents / administration & dosage, therapeutic use* Ventricular Dysfunction, Right / drug therapy*, etiology |
| Chemical | |
Reg. No./Substance:
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0/Vasodilator Agents; 10102-43-9/Nitric Oxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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