Document Detail

Nitric oxide in preterm infant with pulmonary hypoplasia.
MedLine Citation:
PMID:  15163873     Owner:  NLM     Status:  MEDLINE    
Premature infants with hypoplastic lungs may have elevated pulmonary vascular resistance with right to left shunt across ductus arteriosus and/or foramen ovale. Inhaled nitric oxide (NO) being selective pulmonary vasodilator without significant effects on systemic circulation can potentially reverse this shunt. The authors herewith report a case of a premature infant with severe hypoxemic respiratory failure after preterm premature prolonged rupture of membranes leading to oligohydramnios and pulmonary hypoplasia that was treated successfully with NO and describe the neurodevelopmental outcome at 1 year of age.
Nandkishor S Kabra; Martin R Kluckow; Jane Powell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  71     ISSN:  0019-5456     ISO Abbreviation:  Indian J Pediatr     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-05-27     Completed Date:  2004-07-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  427-9     Citation Subset:  IM    
Department of Neonatology and University of Sydney, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
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MeSH Terms
Administration, Inhalation
Child Development
Follow-Up Studies
Infant, Newborn
Infant, Premature*
Nitric Oxide / therapeutic use*
Persistent Fetal Circulation Syndrome / diagnosis*,  therapy*
Pulmonary Gas Exchange
Respiratory Distress Syndrome, Newborn / diagnosis,  therapy*
Respiratory Function Tests
Risk Assessment
Tomography, X-Ray Computed
Treatment Outcome
Reg. No./Substance:
10102-43-9/Nitric Oxide

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