Document Detail

Nitric oxide for the evaluation and treatment of pulmonary hypertension in congenital heart disease.
MedLine Citation:
PMID:  9456484     Owner:  NLM     Status:  MEDLINE    
The use of inhaled nitric oxide as a selective pulmonary vasodilator has expanded to include patients with congenital heart disease and pulmonary hypertension. The therapeutic and diagnostic roles of inhaled nitric oxide offer additional alternatives and benefits to these patients with pulmonary hypertension, particularly in the postoperative setting. This article reviews the background, mechanism of action, toxicities, and current clinical applications of inhaled nitric oxide in the child with congenital heart disease and pulmonary hypertension.
J P Kovalchin; A R Mott; K L Rosen; T F Feltes
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital     Volume:  24     ISSN:  0730-2347     ISO Abbreviation:  Tex Heart Inst J     Publication Date:  1997  
Date Detail:
Created Date:  1998-03-18     Completed Date:  1998-03-18     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  8214622     Medline TA:  Tex Heart Inst J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  308-16     Citation Subset:  IM    
Lillie Frank Abercrombie Section of Cardiology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
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MeSH Terms
Administration, Inhalation
Heart Defects, Congenital / complications*,  surgery
Hypertension, Pulmonary* / diagnosis,  etiology,  therapy
Infant, Newborn
Nitric Oxide / administration & dosage,  adverse effects,  diagnostic use,  physiology,  therapeutic use*
Vasodilator Agents / administration & dosage,  adverse effects,  diagnostic use,  therapeutic use*
Reg. No./Substance:
0/Vasodilator Agents; 10102-43-9/Nitric Oxide

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