Document Detail

Nitric oxide enhancement and blood pressure decrease in patients with metabolic syndrome using soy protein or fish oil.
MedLine Citation:
PMID:  20857058     Owner:  NLM     Status:  In-Process    
OBJECTIVE: To verify the effects of fish oil and soy on nitric oxide (NO) and blood pressure in patients with metabolic syndrome (MS).
SUBJECTS AND METHODS: Sixty women with MS were investigated in a parallel randomized design study. The first group maintained their usual diet; the second group received 25 g/day of soy; the third group received 3 g/day of n-3 fatty acids, and the fourth group the same amount previously cited of n-3 fatty acids and soy.
RESULTS: Serum nitric oxide metabolites showed significant increase after 90 days in the fish oil and soy groups. Systolic pressure reduced after 45 days of treatment with fish oil, whereas diastolic pressure decreased significantly throughout the study in the soy group.
CONCLUSIONS: NO increase and blood pressure reduction with fish oil or soy protein reinforce the importance of the influence of NO on blood pressure in patients with MS.
Andréa Name Colado Simão; Marcell Alysson Batisti Lozovoy; Tathiana Name Colado Simão; Jane Bandeira Dichi; Tiemi Matsuo; Isaias Dichi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Arquivos brasileiros de endocrinologia e metabologia     Volume:  54     ISSN:  1677-9487     ISO Abbreviation:  Arq Bras Endocrinol Metabol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-09-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0403437     Medline TA:  Arq Bras Endocrinol Metabol     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  540-5     Citation Subset:  IM    
Departamento de Patologia, Universidade Estadual de Londrina, PR, Brazil.
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