Document Detail


Nitrendipine therapy in asthmatic subjects.
MedLine Citation:
PMID:  2223429     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nitrendipine was given to eight patients with chronic stable asthma prior to a histamine challenge study and compared in a double-blind cross-over fashion with placebo. There were no significant differences in either the bronchoconstrictor effects of histamine, or in oxygen saturation during the histamine challenges, suggesting that nitrendipine should be safely tolerated if used to treat hypertension in patients with airflow obstruction.
Authors:
E M Mulloy; P Cormie; J Harvey; J E Marley
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  British journal of clinical pharmacology     Volume:  30     ISSN:  0306-5251     ISO Abbreviation:  Br J Clin Pharmacol     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1990-12-04     Completed Date:  1990-12-04     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7503323     Medline TA:  Br J Clin Pharmacol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  493-5     Citation Subset:  IM    
Affiliation:
Ham Green Hospital, Pill, Bristol.
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MeSH Terms
Descriptor/Qualifier:
Adult
Asthma / complications,  drug therapy*
Double-Blind Method
Female
Histamine / pharmacology
Humans
Hypertension / complications
Male
Maximal Expiratory Flow Rate / drug effects
Middle Aged
Nitrendipine / therapeutic use*
Oxygen / metabolism
Chemical
Reg. No./Substance:
39562-70-4/Nitrendipine; 51-45-6/Histamine; 7782-44-7/Oxygen
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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