Document Detail


Nitrate anaphylaxis.
MedLine Citation:
PMID:  10923609     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Nitrate and nitrite salts are commonly used to preserve and sustain color in a number of processed meats. To date there have been no described cases of anaphylaxis to either nitrates or nitrites in the literature. OBJECTIVE: We report a patient with anaphylaxis to nitrates and nitrites documented by double-blind, placebo-controlled capsule challenge. METHODS: A 22-year-old previously well male, presented to a tertiary referral center with a 4-year history of recurrent anaphylaxis after eating take-out food. No further episodes occurred while adhering to a strict elimination diet. We performed a double-blind, placebo-controlled capsule challenge both with food substances and starch placebo. These occurred in a hospital setting with full resuscitative procedures available. RESULTS: An acute anaphylactic reaction occurred following a challenge to nitrates and nitrites. Generalized allergic reactions were observed on separate occasions following administration of artificial colorings and metabisulfite. There was a mild urticarial reaction following salicylates. He was placed on a diet free of sulfites, nitrates, nitrites, and low in salicylates and he has had no further reactions. A computer based search of the Medline, Current Contents and EMBASE databases found no previously reported cases of urticaria, angioedema, or anaphylaxis to either nitrates or nitrites. CONCLUSION: The ingestion of processed meats containing nitrate or nitrite salts may be associated with angioedema and anaphylaxis and should be considered when investigating patients with suspected food allergy.
Authors:
C A Hawkins; C H Katelaris
Related Documents :
6391289 - Immunochemistry of food antigens.
12762659 - Highly enantioselective deracemization of linear and vaulted biaryl ligands.
20525159 - Potential adverse and allergic reactions from complementary and alternative medicine an...
22128549 - Effects of mixture ratio on anaerobic co-digestion with fruit and vegetable waste and f...
16183569 - Fluorescence from the maillard reaction and its potential applications in food science.
22062559 - The effect of modified atmosphere packaging with carbon monoxide on the storage quality...
7612309 - Organochlorine compound residues in human milk in the united kingdom 1989-1991.
7979339 - Food aversion induced by area postrema ablation.
23839799 - To what extent do food preferences explain the trophic position of heterotrophic and mi...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology     Volume:  85     ISSN:  1081-1206     ISO Abbreviation:  Ann. Allergy Asthma Immunol.     Publication Date:  2000 Jul 
Date Detail:
Created Date:  2000-08-08     Completed Date:  2000-08-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9503580     Medline TA:  Ann Allergy Asthma Immunol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  74-6     Citation Subset:  IM    
Affiliation:
Immunology Registrar, Department of Clinical Immunology and Allergy, Westmead Hospital, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Anaphylaxis / chemically induced*
Angioedema / immunology
Dyspnea / immunology
Face
Flushing / immunology
Food Hypersensitivity / etiology
Humans
Male
Nausea / immunology
Nitrates / adverse effects*
Tongue
Vomiting / immunology
Chemical
Reg. No./Substance:
0/Nitrates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Allergic bronchopulmonary aspergillosis as presenting sign of cystic fibrosis in an elderly man.
Next Document:  Identification of allergenic proteins in condoms by immunoenzymatic methods.