Document Detail


Nitazoxanide: clinical studies of a broad-spectrum anti-infective agent.
MedLine Citation:
PMID:  18041899     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nitazoxanide is a new compound with broad-spectrum activity against numerous intestinal protozoa, helminths and anaerobic bacteria. It is approved for the treatment of diseases caused by Giardia intestinalis and Cryptosporidium species. The drug is well tolerated, with few side effects and requires a short course of treatment. Further investigations regarding its use in patients with AIDS is needed. Nitazoxanide represents a significant advance in the treatment of intestinal parasitic infections worldwide.
Authors:
Saima Aslam; Daniel M Musher
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Future microbiology     Volume:  2     ISSN:  1746-0921     ISO Abbreviation:  Future Microbiol     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-11-28     Completed Date:  2008-01-31     Revised Date:  2010-12-30    
Medline Journal Info:
Nlm Unique ID:  101278120     Medline TA:  Future Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  583-90     Citation Subset:  IM    
Affiliation:
Michael E DeBakey VA Medical Center, Section of Infectious Diseases, Room 4B-370, 2002 Holcombe Blvd, Houston, TX 77030, USA. saslam@bcm.tmc.edu
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MeSH Terms
Descriptor/Qualifier:
AIDS-Related Opportunistic Infections / drug therapy*
Acquired Immunodeficiency Syndrome
Antiparasitic Agents / pharmacology,  therapeutic use*
Humans
Parasitic Diseases / drug therapy
Thiazoles / pharmacology,  therapeutic use*
Chemical
Reg. No./Substance:
0/Antiparasitic Agents; 0/Thiazoles; 55981-09-4/nitazoxanide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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