Document Detail


Nippostrongylus brasiliensis: histochemical changes in the composition of mucins in goblet cells during infection in rats.
MedLine Citation:
PMID:  3338549     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Changes in the quality of mucins in jejunal goblet cells were investigated during an infection with Nippostrongylus brasiliensis in rats. At 10 days after infection, when proliferative activity in the crypts is excessive and both crypts and villi are characterized by hyperplasia of goblet cells, the histochemical composition of the population of goblet cells in comparison with controls shows a marked increase in crypt and villous goblet cells containing neutral mucins. At 15 days after infection both crypts and villi display a significant increase in goblet cells containing acid mucin and decrease in goblet cells containing neutral mucin. The acid mucins in crypt and villous goblet cells on day 15 appear to be sulphomucins predominantly, whereas in controls sialomucin-containing goblet cells dominate both in the crypts and on the villi. These experiments establish that the explusion of N. brasiliensis from the intestine of the rat coincides not only with quantitative, but also with remarkable qualitative changes in the histochemical composition of mucins in goblet cells.
Authors:
J F Koninkx; M H Mirck; H G Hendriks; J M Mouwen; J E van Dijk
Related Documents :
6462619 - Possible mechanisms for the loss of goblet cells in mucin-deficient disorders.
15499179 - Factors affecting glucuronidation activity in caco-2 cells.
10564109 - Glucocorticoids have pleiotropic effects on small intestinal crypt cells.
1786079 - Extrathymic differentiation of intraepithelial lymphocytes: generation of a separate an...
9972649 - Immunohistochemical study of endocrine cells in the gastrointestinal tract of the phili...
8522069 - Two stages of enteropathogenic escherichia coli intestinal pathogenicity are up and dow...
4316229 - Nonproducing state of rous sarcoma cells: its contagiousness in chicken cell cultures.
9054499 - Oncogenic ras provokes premature cell senescence associated with accumulation of p53 an...
19216769 - Rapid glycation with d-ribose induces globular amyloid-like aggregations of bsa with hi...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experimental parasitology     Volume:  65     ISSN:  0014-4894     ISO Abbreviation:  Exp. Parasitol.     Publication Date:  1988 Feb 
Date Detail:
Created Date:  1988-03-02     Completed Date:  1988-03-02     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0370713     Medline TA:  Exp Parasitol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  84-90     Citation Subset:  IM    
Affiliation:
Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Utrecht, The Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Histocytochemistry
Intestinal Mucosa / metabolism,  pathology
Jejunum / metabolism,  pathology*
Male
Mucins / metabolism*
Nematode Infections / metabolism*,  pathology
Nippostrongylus
Rats
Chemical
Reg. No./Substance:
0/Mucins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Hymenolepis muris-sylvaticae and H. microstoma: immunological cross-reaction in mice.
Next Document:  Trichobilharzia ocellata: interference with endocrine control of female reproduction of Lymnaea stag...